The Madame expansion was the final title in the "white cycle" of T.I.M.E. Stories. This will be succeeded by the "blue cycle", which differs vastly from the game's initial incarnation.
Each scenario will be a standalone item that can be played in any order relative to other titles in the blue cycle. While the white cycle focused on items, the blue cycle focuses more on characters. Each receptacle in a scenario - that is, the body of the being you'll inhabit when you move forward, backward, or sideways in time - will have its own deck of cards, with the nature of these characters having more importance during gameplay. When you meet someone in a scenario, for example, that individual will likely respond to player A differently than they will for player B. In one case, you might get information from a source; in another case, the source might run away or attack you or lie. In addition to the personality of the receptacles, the characters within a scenario - the agents represented by the 2-4 players - will have backgrounds of their own that might interact or interfere with missions in different ways.